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November 23, 2003

Risk Of Positive Test By Age

Risk to test positive for an HD mutation in at-risk adults

Probability that a person with an apriori 50% Risk for HD will test
positive for an HD mutation if He/She remains asymptomatic at a given age

Age (Years)
Probability of
an HD
Mutation (%)
20 yrs
49.6%
22.5 yrs
49.3%
25 yrs
49%
27.5 yrs
48.4%
30 yrs
47.6%
32.5 yrs
46.6%
35 yrs
45.5%
37.5 yrs
44.2%
40 yrs
42.5%
42.5 yrs
40.3%
45 yrs
37.8%
47.5 yrs
34.8%
50 yrs
31.5%
52.5 yrs
27.8%
55 yrs
24.8%
57.5 yrs
22.1%
60 yrs
22.1%
62.5 yrs
18.7%
65 yrs
12.8%
67.5 yrs
10.8%
70 yrs
6.2%
72.5 yrs
4.6%

From Harper & Newcombe 1992

Copyright© 1993-2003, All Rights Reserved
www.genetests.org

Children's Health System and University of Washington, Seattle

Posted by Dave at November 23, 2003 07:17 AM

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