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May 22, 2004
One More - Rapamycin
This time from the Better Human's website:
"(Rapamycin) was isolated in 1975 from a strain of bacteria found in soil on Easter Island, and is now marketed as "Rapamune" by Madison, New Jersey-based Wyeth, having received US Food and Drug Administration approval in 1999.
Rubinsztein and colleagues are interested in studying the effects of rapamycin for inducing autophagy—the feeding of the body upon itself—to clear mutant huntingtin from the body.
Rapamycin has been found to cause in cells a physiological response akin to nutrient starvation, and to induce autophagy even in cells growing in a nutrient-rich culture..."
"They found that rapamycin protected against neurodegeneration in a fly model of the disease and improved performance on four different behavioral tasks in a mouse model of the disease.
The researchers are now building on and refining their studies before considering human trials."
Posted by Dave at May 22, 2004 03:37 PM
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